Definition of big eyes:
(N) :
a 2014 American biographical comedy drama film directed by Tim Burton, written by Scott Alexander and Larry Karaszewski, and starring Amy Adams and Christoph Waltz.
(N) :
"Big Eyes" is a song by American singer and songwriter Lana Del Rey.
(N) :
(– after 1542) a Wichita woman who acted as a guide for Francisco Vázquez de Coronado's expedition exploring what is now the southwestern United States.