We don't have any synonyms for fed-up yet.
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Definition of fed-up:
(n) :
(Canada, in the plural) The Canadian federal government.
(n) :
(MLE, MTE, slang) A police officer.
(n) :
(slang, derogatory) A federal government officer or official.
(n) :
(weightlifting, slang) A federation in which powerlifters organize to compete.
(n) :
(US, economics, banking, nonstandard) Federal Reserve System. Alternative spelling of Fed.
(v) :
Clipping of federate. [To unite in a federation.]