Definition of lamest:
(adj) :
(colloquial) Unconvincing or unbelievable.
(adj) :
(colloquial) Uncool, uninteresting, or unfunny.
(adj) :
(especially of an animal) Unable to walk properly because of a problem with one's feet or legs.
(adj) :
(of a limb, especially a foot or leg) That cannot be moved properly.
(v) :
(transitive) To cause (a person or animal) to become lame.
(adj) :
(dated, now offensive) Physically disabled.