Definition of nukes:
(n) :
A nuclear weapon.
(n) :
(by extension) Something that destroys or negates, especially on a catastrophic scale.
(n) :
A nuclear power station.
(n) :
(nautical) A vessel such as a ship or submarine running on nuclear power.
(n) :
A person (such as a sailor in a navy or a scientist) who works with nuclear weapons or nuclear power.
(v) :
(transitive, chiefly Canada, US, colloquial) To use a nuclear weapon on (a target).