Definition of puffers:
(n) :
Any of several poisonous fish, of the family Tetraodontidae, which have the ability to inflate their bodies when in danger.
(n) :
(fashion) An insulated puffy jacket, such as a down jacket.
(n) :
A manually-operated inhaler.
(n) :
Someone or something that puffs.
(n) :
(slang) A car left idling to warm up, emitting steam from the rear.
(n) :
(dated, childish) A train; a locomotive, usually one that is steam-powered.