Definition of setbacks:
(n) :
An obstacle, delay, disadvantage, or blow (an adverse event which slows down, or prevents progress towards a desired outcome).
(n) :
(by extension) Any adverse event, defeat, or impediment of progress.
(n) :
(US) The required distance between a structure and a road.
(n) :
(architecture) A step-like recession in a wall.
(n) :
An offset to the temperature setting of a thermostat to cover a period when more or less heating is required than usual.
(n) :
(possibly archaic) A backset; a countercurrent; an eddy.