Definition of simes:
(n) :
(video games) Any of the characters in the video game The Sims, which simulates aspects of a human social environment.
(n) :
A male given name, diminutive of Simeon and Simon.
(n) :
A Scottish surname transferred from the given name derived from the given name.
(n) :
A Simeonite (follower of Charles Simeon).
(n) :
(by extension) A person with Methodist tendencies.
(n) :
(often derogatory) Someone who is, or is accused of, acting like a bumbling fool.